Stay at Quality Inn hotels in Winston-Salem, NCMake your acquaintance with the other “Twin City” when you stay at one of our Quality Inn hotels in Winston-Salem, NC. The dual city is also nicknamed and "City of the Arts and Innovation" for its numerous theaters, its high-tech industries and its culture. Winston-Salem is home to the University of North Carolina School of the Arts and the Stevens Center for the Performing Arts. Local historical attractions include the Reynolda House Museum of American Art, the former home of tobacco baron R.J. Reynolds and Old Salem Museums & Gardens. For families staying in Winston-Salem, Quality Inn hotels are close to the Children's Museum of Winston-Salem and SciFi Science Museum. Be sure to book a room at one of our affordable hotels in Winston-Salem today to take advantage of our inviting housing, warm hospitality and attentive service during your stay. Book online now to guarantee your reservation.